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Sedation and Anesthesia

Epinephrine in dental anesthetic

Epinephrine is a drug added to many dental numbing solutions. It narrows blood vessels near the injection site, a step used together with the anesthetic.

Many dental anesthetics contain a small amount of epinephrine, also called adrenaline. It is a vasoconstrictor, which means it narrows blood vessels. The most common forms are 1:50,000, 1:100,000, and 1:200,000.

Narrowed vessels carry less blood to the area. A vasoconstrictor is often used with a local anesthetic such as articaine. It is part of how a nerve block is made to numb the area.

Tell your dentist about your health history and any medicines you take. Your dentist can then choose the right solution for you.

Related terms

Sources

  1. NIH PMC: Articaine (4%) with epinephrine (1:100000 or 1:200000) for inferior alveolar nerve block
  2. NIH PMC: Articaine (4%) with epinephrine (1:100000 or 1:200000) for inferior alveolar nerve block
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